Improving understanding of acute kidney injury in older veterans
Advancing the Phenotyping of Acute Kidney Injury for the Million Veterans Program
This study is looking at how genetics might affect the risk of serious kidney problems in older veterans, with the hope of finding better ways to treat and help those who develop acute kidney injury.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11291839 on NIH RePORTER |
What this research studies
This research focuses on acute kidney injury (AKI), a serious condition that can lead to long-term kidney damage and other health issues, particularly in older veterans. The study aims to enhance the understanding of the genetic factors that contribute to the risk of developing intrinsic AKI, which is the most severe form of the condition. By employing advanced techniques like genome-wide association studies and improved phenotyping methods, the research seeks to identify distinct subtypes of AKI to better tailor treatments. The ultimate goal is to translate these findings into effective clinical practices that can improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans aged 65 and older who are at risk for acute kidney injury.
Not a fit: Patients under the age of 65 or those without risk factors for acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for acute kidney injury in older veterans, potentially reducing mortality and improving quality of life.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to acute kidney injury, but this study aims to take a novel approach by focusing on a larger, more diverse veteran population.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Siew, Edward D — Veterans Health Administration
- Study coordinator: Siew, Edward D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.