Improving understanding of acute kidney injury in older veterans
Advancing the Phenotyping of Acute Kidney Injury for the Million Veterans Program
This study is looking at how genetics might affect the risk of older veterans developing a serious kidney problem called acute kidney injury, with the goal of finding better ways to treat it and help those who are affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11281231 on NIH RePORTER |
What this research studies
This research focuses on acute kidney injury (AKI), a serious condition that can lead to long-term kidney damage and other health issues, particularly in older veterans. The study aims to better understand the genetic factors that contribute to the risk of developing intrinsic AKI, which is the most severe form of this condition. By using advanced techniques like genome-wide association studies and improved phenotyping methods, the research seeks to identify distinct subtypes of AKI that could lead to more effective treatments. This work is crucial for developing targeted interventions that could improve health outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans aged 65 and older who are at risk for acute kidney injury.
Not a fit: Patients under the age of 65 or those without risk factors for acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for acute kidney injury in older veterans, ultimately improving their quality of life.
How similar studies have performed: Previous research has shown promise in understanding genetic factors related to acute kidney injury, but this study aims to advance the field with a more comprehensive approach.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Siew, Edward D — Veterans Health Administration
- Study coordinator: Siew, Edward D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.