Improving understanding of acute kidney injury in older veterans
Advancing the Phenotyping of Acute Kidney Injury for the Million Veterans Program
['FUNDING_OTHER'] · VETERANS HEALTH ADMINISTRATION · NIH-11280838
This study is looking at how genetics and biology affect the risk of serious kidney problems in older veterans, with the hope of finding better ways to treat these issues and help patients feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VETERANS HEALTH ADMINISTRATION (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11280838 on ClinicalTrials.gov |
What this research studies
This research focuses on acute kidney injury (AKI), a serious condition that can lead to long-term kidney damage and other health issues, particularly in older veterans. The study aims to enhance the understanding of the genetic and biological factors that contribute to the risk of developing intrinsic AKI, which is the most severe form of the condition. By employing advanced techniques like genome-wide association studies and improved phenotyping methods, the research seeks to identify distinct subtypes of AKI that could lead to better-targeted treatments. The ultimate goal is to translate these findings into clinical practice to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans aged 65 and older who are at risk for acute kidney injury.
Not a fit: Patients who are younger than 65 or do not have risk factors for acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and management strategies for acute kidney injury in older veterans.
How similar studies have performed: While there have been limited studies on acute kidney injury, this research aims to explore novel approaches that have not yet been widely tested.
Where this research is happening
NASHVILLE, UNITED STATES
- VETERANS HEALTH ADMINISTRATION — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIEW, EDWARD D — VETERANS HEALTH ADMINISTRATION
- Study coordinator: SIEW, EDWARD D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: acute kidney injury