Improving understanding of acute kidney injury in older veterans
Advancing the Phenotyping of Acute Kidney Injury for the Million Veterans Program
This study is looking at how genetics might affect the risk of serious kidney problems in older veterans, with the hope of finding better ways to treat and help those who are at risk for kidney injury.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10782436 on NIH RePORTER |
What this research studies
This research focuses on acute kidney injury (AKI), a serious condition that can lead to long-term kidney damage and other health complications, particularly in older veterans. The study aims to better understand the genetic factors and mechanisms that contribute to the risk of developing intrinsic AKI, which is the most severe form of the condition. By employing advanced techniques like genome-wide association studies and improved phenotyping methods, the research seeks to identify distinct subtypes of AKI that could lead to more effective treatments. The ultimate goal is to enhance patient outcomes by providing targeted interventions based on individual risk profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans aged 65 and older who are at risk for acute kidney injury.
Not a fit: Patients who are younger than 65 or do not have risk factors for acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for acute kidney injury, significantly improving health outcomes for older veterans.
How similar studies have performed: While there have been limited studies on acute kidney injury, this research aims to fill critical gaps and may provide novel insights that have not been extensively explored before.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Siew, Edward D — Veterans Health Administration
- Study coordinator: Siew, Edward D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.