Improving ultrasound imaging to better understand atherosclerotic plaque progression and rupture risk

Super Resolution Ultrasound Imaging of Vasa Vasorum to Characterize the Progression of Atherosclerotic Plaques and Predict Rupture Vulnerability

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11021005

This study is testing a new ultrasound method to take clear pictures of tiny blood vessels linked to plaque buildup in your arteries, which can help doctors better understand your heart health and track any changes over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11021005 on NIH RePORTER

What this research studies

This research focuses on developing a new ultrasound imaging technique to visualize the small blood vessels associated with atherosclerotic plaques, which can lead to heart attacks and strokes. By using a noninvasive approach, the study aims to provide high-resolution images that can help track the progression of these plaques over time. The methodology involves advanced imaging technology that overcomes current limitations in visualizing these critical structures. Patients may benefit from improved risk assessment and monitoring of their cardiovascular health.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk for cardiovascular diseases, particularly those with known atherosclerosis or related conditions.

Not a fit: Patients who do not have atherosclerotic disease or are not at risk for cardiovascular events may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prediction and prevention of heart attacks and strokes by identifying vulnerable atherosclerotic plaques.

How similar studies have performed: Previous studies have shown promise in using advanced imaging techniques for vascular assessment, indicating potential success for this novel approach.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions acute coronary syndromeAnimal Disease Models
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.