Improving treatments for brain cancer patients
Official title: SPORE for Translational Approaches to Brain Cancer
Funded at Northwestern University at Chicago · NIH-10898565 · Data updated 2026-11-12
This study is looking for better ways to treat brain tumors, especially glioblastoma, by bringing together a team of experts to find new treatment options that could help patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 17, 2018 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $2,076,151 |
| NIH project number | 5P50CA221747-07 |
| Project ID | NIH-10898565 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with glioblastoma or other types of brain tumors.
✕Less likely to help
Patients with brain tumors that are not glioblastoma or those who are not eligible for experimental treatments may not benefit from this research.
What this research studies
This research focuses on enhancing outcomes for patients with brain tumors, particularly glioblastoma, which is known for its aggressive nature and poor survival rates. The team of experienced researchers is employing a multidisciplinary approach to explore new treatment strategies that can overcome the limitations of current therapies. By collaborating and sharing expertise, they aim to develop innovative methods to effectively target and treat this challenging cancer. Patients may benefit from novel therapeutic options that are being investigated through this collaborative effort.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and quality of life for brain cancer patients.
How similar studies have gone: Previous research has shown promise in developing new therapies for glioblastoma, but this approach aims to build on those findings with a team-based strategy.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Lesniak, Maciej S — Northwestern University at Chicago
- Study coordinator: Lesniak, Maciej S
Related research
Other NIH-funded projects on the same topics.
-
Social connections and quality of life for kids who survived brain cancer
This project follows pediatric brain cancer survivors as they grow into adults to understand how their social connections affect their happiness and mental well-being.
-
Brain cancer and brain-glia communication: how tumor cells and microglia talk to each other to drive gbm growth
A patient-facing look at how GBM tumors may manipulate brain immune cells to grow, and how understanding this communication could lead to new treatments.
-
Clarified imaging reports to reduce anxiety for adult survivors of pediatric brain cancer
Adult survivors of pediatric brain cancer may get anxious about scan results, and clearer imaging reports delivered through patient portals could help reduce worry and improve understanding.
-
MRI-guided brain tumor surgery robot to improve laser ablation
A new MRI-compatible robotic system helps precise, real-time laser treatment for brain tumors inside the MRI suite.
-
Brain cancer therapies to help kids and adults with glioblastoma and medulloblastoma
A large NIH grant supports translating promising brain cancer therapies from the lab into patient trials to help people with glioblastoma and medulloblastoma.
-
Brain cancer: Translational approaches to improve outcomes for glioblastoma patients
A team at Northwestern is working on better ways to treat glioblastoma, the deadliest brain cancer, with a focus on translating discoveries into real therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.