Improving treatments for atherosclerosis through personalized lesion modification
Personalized lesion modification optimizes atherosclerosis intervention
['FUNDING_R01'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11002670
This study is looking at new ways to improve treatment for atherosclerosis by personalizing how we prepare and treat plaque in blood vessels, using advanced techniques to help doctors provide better care for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11002670 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the treatment of atherosclerosis by developing personalized approaches to modify lesions in blood vessels. The team will investigate advanced techniques, such as orbital atherectomy and lithotripsy, to optimize the preparation of complex plaques before procedures like angioplasty. By utilizing intravascular imaging and creating validated criteria for treatment outcomes, the research aims to provide better guidance for interventionalists, ultimately improving patient care. The goal is to understand the biology of lesion modification and predict functional outcomes based on imaging.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with atherosclerosis who may require interventional procedures to treat complex lesions.
Not a fit: Patients with non-atherosclerotic cardiovascular conditions or those who do not require interventional treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with atherosclerosis, potentially reducing complications and improving recovery.
How similar studies have performed: Previous research has shown promise in using advanced imaging and lesion modification techniques, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: EDELMAN, ELAZER R — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: EDELMAN, ELAZER R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease, atherosclerotic coronary disease