Improving treatment planning for narrowing of peripheral pulmonary arteries in congenital heart disease
Official title: Uncertainty aware virtual treatment planning for peripheral pulmonary artery stenosis
Funded at Stanford University · NIH-10844440 · Data updated 2026-11-12
This study is working on new ways to help doctors plan better treatments for patients with narrowing of the blood vessels in the lungs, which is a common issue for those with congenital heart disease, so they can get more effective care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $676,028 |
| NIH project number | 5R01HL167516-02 |
| Project ID | NIH-10844440 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants and children diagnosed with congenital heart disease, specifically those experiencing peripheral pulmonary artery stenosis.
✕Less likely to help
Patients with other forms of heart disease not involving peripheral pulmonary artery stenosis may not benefit from this research.
What this research studies
This research focuses on developing advanced modeling techniques to enhance treatment planning for patients with peripheral pulmonary artery stenosis, a common complication in congenital heart disease. The approach combines a mechanistic multiscale model with real-time uncertainty-aware digital tools to aid clinicians in making informed decisions about patient care. By addressing the complexities of this condition, the research aims to improve outcomes for patients who often face ineffective traditional treatments. The goal is to create a comprehensive decision support system that can guide interventions more effectively.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for patients with peripheral pulmonary artery stenosis, potentially reducing complications and improving long-term health outcomes.
How similar studies have gone: Previous research has shown promise in using advanced modeling techniques for similar conditions, indicating potential for success in this novel approach.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Marsden, Alison L — Stanford University
- Study coordinator: Marsden, Alison L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.