Improving treatment planning for narrowing of peripheral pulmonary arteries in congenital heart disease

Uncertainty aware virtual treatment planning for peripheral pulmonary artery stenosis

NIH-funded research Stanford University · NIH-10844440

This study is working on new ways to help doctors plan better treatments for patients with narrowing of the blood vessels in the lungs, which is a common issue for those with congenital heart disease, so they can get more effective care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10844440 on NIH RePORTER

What this research studies

This research focuses on developing advanced modeling techniques to enhance treatment planning for patients with peripheral pulmonary artery stenosis, a common complication in congenital heart disease. The approach combines a mechanistic multiscale model with real-time uncertainty-aware digital tools to aid clinicians in making informed decisions about patient care. By addressing the complexities of this condition, the research aims to improve outcomes for patients who often face ineffective traditional treatments. The goal is to create a comprehensive decision support system that can guide interventions more effectively.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants and children diagnosed with congenital heart disease, specifically those experiencing peripheral pulmonary artery stenosis.

Not a fit: Patients with other forms of heart disease not involving peripheral pulmonary artery stenosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment strategies for patients with peripheral pulmonary artery stenosis, potentially reducing complications and improving long-term health outcomes.

How similar studies have performed: Previous research has shown promise in using advanced modeling techniques for similar conditions, indicating potential for success in this novel approach.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alagille SyndromeAlagille-Watson Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.