Improving treatment options for multiple sclerosis in veterans using biomaterials
Official title: Biomaterials-Enabled Delivery of Immunometabolic Modulators to Improve Treatment Options for Multiple Sclerosis in Veterans
Funded at Baltimore VA Medical Center · NIH-10720881 · Data updated 2026-11-12
This study is looking at new ways to treat multiple sclerosis (MS) in veterans by using special materials to deliver targeted treatments that could work better and have fewer side effects, all with the goal of improving their quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baltimore VA Medical Center NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 30, 2023 |
| Project end | September 30, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK2BX005756-02 |
| Project ID | NIH-10720881 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans diagnosed with multiple sclerosis who are seeking new treatment options.
✕Less likely to help
Patients with other autoimmune diseases or those not diagnosed with multiple sclerosis may not benefit from this research.
What this research studies
This research focuses on developing new treatment methods for multiple sclerosis (MS), particularly in veterans who are disproportionately affected by this autoimmune disease. The approach involves using biomaterials to deliver immunometabolic modulators that can target specific immune responses, potentially improving treatment efficacy while minimizing side effects. By exploring the role of cell metabolism in immune function, the research aims to create therapies that are more effective and require fewer doses than current options. This innovative strategy seeks to enhance the quality of life for patients suffering from MS.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatment options for veterans with multiple sclerosis.
How similar studies have gone: Previous research has shown promise in using metabolic modulators for treating autoimmune conditions, indicating potential success for this novel approach.
Where this research is happening
-
Baltimore VA Medical Center
Baltimore, United States Active
Researchers
- Principal investigator: Kapnick, Senta — Baltimore VA Medical Center
- Study coordinator: Kapnick, Senta
Related research
Other NIH-funded projects on the same topics.
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-
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Promoting brain repair in MS with a natural compound that nudges neural stem cells
A researcher is testing a natural-product–based compound that may help people with multiple sclerosis repair nerve damage by guiding brain stem cells to become neurons and myelin-producing cells.
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Targeted B cell tolerance therapy for multiple sclerosis using Ace-DEX microparticles
A new therapy using tiny biopolymer particles given through the vein aims to retrain B cells to tolerate the immune system in people with multiple sclerosis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.