Improving treatment for glioblastoma using nanotechnology and thermal therapy
Nanotherapeutic enhancement of interstitial thermal therapy for glioblastoma
['FUNDING_R01'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10988245
This study is looking at new ways to make heat treatment for glioblastoma, a tough type of brain tumor, work better by using special tools and techniques to help deliver medicine more effectively, and it invites patients to join trials to see how these exciting new methods can improve their treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10988245 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the effectiveness of thermal therapy for glioblastoma, a highly aggressive brain tumor. By utilizing advanced techniques like MRI-guided laser probes, the study aims to improve drug delivery and treatment outcomes for patients with this challenging condition. The approach involves using nanotherapeutics to sensitize tumors to radiation, potentially increasing the efficacy of existing treatments. Patients may be involved in clinical trials that explore these innovative therapies and their effects on tumor response.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with glioblastoma who have limited treatment options due to the aggressive nature of the disease.
Not a fit: Patients with other types of brain tumors or those who are not eligible for thermal therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve survival rates and quality of life for patients with glioblastoma.
How similar studies have performed: Preliminary results from similar approaches using laser interstitial thermal therapy have shown promise, indicating potential for success in this novel application.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WOODWORTH, GRAEME F — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: WOODWORTH, GRAEME F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury, Brain Cancer