Improving the use of effective treatments for acute respiratory failure
Official title: Strengthening implementation science in Acute Respiratory Failure using multilevel analysis of existing data
Funded at Johns Hopkins University · NIH-10888386 · Data updated 2026-11-12
This study is looking at ways to help doctors use the best treatments for patients with acute respiratory failure, a serious condition that many people face, so that more patients can get the care they need to recover in the hospital.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 15, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $124,681 |
| NIH project number | 5R21HL167175-02 |
| Project ID | NIH-10888386 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who experience acute respiratory failure and require mechanical ventilation in an intensive care unit.
✕Less likely to help
Patients who do not experience acute respiratory failure or those who are not admitted to an intensive care unit may not benefit from this research.
What this research studies
This research investigates how to enhance the implementation of evidence-based practices for patients experiencing acute respiratory failure, a condition that affects up to 1 million Americans annually. By analyzing existing data and applying a structured framework, the study aims to identify the best strategies for ensuring that proven treatments are consistently used in clinical settings. The focus is on overcoming barriers that prevent healthcare providers from adopting these life-saving practices, ultimately aiming to improve patient outcomes in intensive care units.
Why it matters
Potential benefit: If successful, this research could lead to more consistent use of effective treatments for acute respiratory failure, potentially saving lives and improving recovery rates.
How similar studies have gone: Previous research has shown that structured implementation strategies can improve the uptake of evidence-based practices in clinical settings, suggesting that this approach has potential for success.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Turnbull, Alison — Johns Hopkins University
- Study coordinator: Turnbull, Alison
Related research
Other NIH-funded projects on the same topics.
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Using a simple breathing test to check lung function after kids’ acute respiratory failure
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Financial hardship in acute respiratory failure patients and their family caregivers
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Understanding which patients and hospital care pathways affect outcomes after ICU vs ward care for ARF and sepsis
A big study using hospital records to figure out which patients with acute respiratory failure and sepsis do best when admitted to ICUs versus general wards.
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Optimizing Time-Limited Trials of Ventilation in Acute Respiration Failure
Aimed at patients with acute respiratory failure, this project looks at how short-term trials of life-support in the ICU can be better planned and communicated.
-
Using a simple breathing test to check how kids recover lung function after severe lung illness
A study will test a quick, noninvasive breathing test called oscillometry to see how well children who survived dangerous lung problems recover over time.
-
Breathing effort and ventilator safety in severe respiratory failure
This research looks at how a person's own breathing effort affects lung and diaphragm injury for adults on ventilators for acute respiratory failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.