Improving the production of beneficial sugars found in human milk
Official title: Scaling-up flow processes for the chemoenzymatic synthesis of a sialylated glycan
Funded at Zymtronix Catalytic Systems, INC. · NIH-10931147 · Data updated 2026-11-12
This study is looking at ways to make more human milk sugars, which are great for babies and can help with gut health and immune issues, so they can be used in baby formulas and treatments for conditions like allergies and autoimmune diseases.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Zymtronix Catalytic Systems, INC. NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | August 7, 2019 |
| Project end | January 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,144,101 |
| NIH project number | 2R44GM134847-02A1 |
| Project ID | NIH-10931147 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include infants who are breastfed, as well as adults suffering from gut inflammatory disorders or autoimmune diseases.
✕Less likely to help
Patients who do not have gut inflammatory disorders, autoimmune diseases, or allergies may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the production of human milk oligosaccharides (HMOs), which are important components of human milk known for their potential health benefits. The approach involves using advanced biomanufacturing techniques to produce these sugars in larger quantities, making them available for use in infant formulas and therapeutic applications. By improving the efficiency of HMO production, the research aims to facilitate their study and application in treating gut inflammatory disorders, autoimmune diseases, and allergies. Patients may benefit from the findings as these sugars could help improve gut health and immune responses.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve gut health and reduce inflammation in patients, particularly infants and those with autoimmune or allergic conditions.
How similar studies have gone: Previous research has shown promise in the use of human milk oligosaccharides for improving gut health, indicating that this approach has potential based on earlier successes.
Where this research is happening
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Zymtronix Catalytic Systems, INC.
Ithaca, United States Active
Researchers
- Principal investigator: Corgie, Stephane Cedric — Zymtronix Catalytic Systems, INC.
- Study coordinator: Corgie, Stephane Cedric
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.