Improving the classification of unexplained strokes using advanced MRI techniques
Quantitative model-based ESUS reclassification using cardiac and cerebral vessel wall MRI
This study is looking to better understand certain types of strokes, especially those that doctors can't easily explain, by using special MRI scans to find hidden problems in the heart and blood vessels, so that we can create more personalized treatment plans to help prevent future strokes for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10918313 on NIH RePORTER |
What this research studies
This research focuses on enhancing the understanding of ischemic strokes, particularly those classified as embolic stroke of undetermined source (ESUS). By utilizing advanced cardiac and cerebral vessel wall MRI, the study aims to identify previously undetected lesions related to atherosclerosis and cardiac issues that may contribute to these strokes. The goal is to improve diagnostic accuracy, allowing for personalized treatment plans that can better prevent recurrent strokes. Patients will undergo MRI scans to help reclassify their stroke type and tailor secondary prevention strategies accordingly.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke classified as ESUS and may have underlying cardiac or vascular conditions.
Not a fit: Patients who have a clear and identifiable cause for their ischemic stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention strategies for patients at risk of recurrent strokes.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to improve stroke classification, indicating potential for success in this approach.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Mossa-Basha, Mahmud — University of Washington
- Study coordinator: Mossa-Basha, Mahmud
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.