Improving the analysis of viruses in human tissue samples
Official title: Viral MEM: Viral Enrichment and Precise Stochastic Quantification with Microbial Context Preservation for Rigorous Virome Analysis of Challenging Human Samples
Funded at California Institute of Technology · NIH-10986859 · Data updated 2026-11-12
This study is working on new ways to find and understand viruses in human tissues, which could help doctors diagnose viral infections better and learn more about how viruses affect our health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California Institute of Technology NIH-funded |
| Lab location | 1 site (Pasadena, United States) |
| Project start | September 20, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $594,934 |
| NIH project number | 1U01DE034199-01 |
| Project ID | NIH-10986859 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with gastrointestinal disorders, particularly those related to viral infections.
✕Less likely to help
Patients without gastrointestinal issues or those not affected by viral infections may not benefit from this research.
What this research studies
This research focuses on enhancing the understanding of the human virome by developing new technologies for analyzing viruses in human tissue samples. It aims to overcome challenges such as contamination from host DNA and low amounts of viral material. The project will create innovative methods for enriching and quantifying viruses, which could lead to better detection and characterization of viral infections. Patients may benefit from improved diagnostic techniques and a deeper understanding of viral roles in health and disease.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and treatments for viral infections in patients.
How similar studies have gone: Previous research has shown promise in similar approaches to virome analysis, indicating potential for success in this innovative methodology.
Where this research is happening
-
California Institute of Technology
Pasadena, United States Active
Researchers
- Principal investigator: Ismagilov, Rustem F — California Institute of Technology
- Study coordinator: Ismagilov, Rustem F
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.