Improving statin use among Veterans at risk for heart disease through genetic testing
Official title: Reducing Veterans' Risk of Atherosclerotic Cardiovascular Disease Through Pharmacogenomics Informed Statin Prescribing
Funded at Ralph H Johnson VA Medical Center · NIH-10750662 · Data updated 2026-11-12
This study is looking to help Veterans who are at high risk for heart problems by using genetic testing to show how their genes affect how well statins work for them, making it easier for them to understand and stick with their treatment for better heart health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ralph H Johnson VA Medical Center NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| NIH project number | 1I01HX003477-01A3 |
| Project ID | NIH-10750662 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Veterans who are at high risk for cardiovascular disease and are currently not taking statins.
✕Less likely to help
Patients who are already effectively managing their cholesterol with statins or those who have contraindications to statin therapy may not benefit from this research.
What this research studies
This research aims to enhance the use of statins among Veterans who are at high risk for cardiovascular disease by utilizing pharmacogenomic testing. The study will provide patients with information about how their genetics affect the efficacy and safety of statins, which may improve their understanding and acceptance of this treatment. By addressing misconceptions and providing tailored information, the goal is to increase the number of Veterans who start and continue taking statins, ultimately leading to better cholesterol management and reduced cardiovascular risk.
Why it matters
Potential benefit: If successful, this research could lead to more Veterans effectively managing their cholesterol levels and reducing their risk of cardiovascular disease.
How similar studies have gone: Previous research has shown that pharmacogenomic testing can improve patient perceptions and increase appropriate statin prescribing, indicating a promising approach.
Where this research is happening
-
Ralph H Johnson VA Medical Center
Charleston, United States Active
Researchers
- Principal investigator: Voora, Deepak — Ralph H Johnson VA Medical Center
- Study coordinator: Voora, Deepak
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.