Improving statin use among Veterans at risk for heart disease through genetic testing

Reducing Veterans' Risk of Atherosclerotic Cardiovascular Disease Through Pharmacogenomics Informed Statin Prescribing

NIH-funded research Ralph H Johnson VA Medical Center · NIH-10750662

This study is looking to help Veterans who are at high risk for heart problems by using genetic testing to show how their genes affect how well statins work for them, making it easier for them to understand and stick with their treatment for better heart health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRalph H Johnson VA Medical Center NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-10750662 on NIH RePORTER

What this research studies

This research aims to enhance the use of statins among Veterans who are at high risk for cardiovascular disease by utilizing pharmacogenomic testing. The study will provide patients with information about how their genetics affect the efficacy and safety of statins, which may improve their understanding and acceptance of this treatment. By addressing misconceptions and providing tailored information, the goal is to increase the number of Veterans who start and continue taking statins, ultimately leading to better cholesterol management and reduced cardiovascular risk.

Who could benefit from this research

Good fit: Ideal candidates for this research are Veterans who are at high risk for cardiovascular disease and are currently not taking statins.

Not a fit: Patients who are already effectively managing their cholesterol with statins or those who have contraindications to statin therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more Veterans effectively managing their cholesterol levels and reducing their risk of cardiovascular disease.

How similar studies have performed: Previous research has shown that pharmacogenomic testing can improve patient perceptions and increase appropriate statin prescribing, indicating a promising approach.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular DiseaseCardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.