Improving sleep to lower diabetes risk

Sleep for Health: A randomized clinical trial examining the effects of cognitive behavioral therapy for insomnia on diabetes risk

NIH-funded research Kaiser Foundation Research Institute · NIH-11289310

This program gives adults with prediabetes and insomnia a six-session online cognitive behavioral therapy for insomnia to see if improving sleep lowers blood sugar.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project IDNIH-11289310 on NIH RePORTER

What this research studies

If you have prediabetes and trouble sleeping, you could join a trial that randomly assigns you to a six-session digital CBT-I program or to an online patient-education website. The study plans to enroll about 300 adults and will collect measures at the start, after 10 weeks (when the program ends), and again at 32 weeks. Researchers will track blood sugar levels, objective and self-reported sleep, and lifestyle factors like diet to see how sleep changes relate to glucose. Participation mainly involves completing the online program and coming in (or providing samples) for blood and sleep measurements on the scheduled visits.

Who could benefit from this research

Good fit: Adults (21 years and older) with prediabetes who also have symptoms of insomnia and can use an online program are the ideal candidates.

Not a fit: People without prediabetes, without insomnia, or those who already have diagnosed type 2 diabetes are unlikely to benefit from this trial’s intervention.

Why it matters

Potential benefit: If successful, this approach could help prevent or delay type 2 diabetes by lowering blood sugar in people with prediabetes through better sleep.

How similar studies have performed: A prior feasibility study showed promising signs that treating insomnia may improve glucose, but this larger randomized trial is the first definitive test in people with prediabetes.

Where this research is happening

Oakland, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.