Improving sickle cell care in Mali through a Pan‑African network

Improving Sickle Cell Disease Care in Mali through Engagement with a Pan-African Sickle Cell Disease Network.

NIH-funded research Univ of Sciences, Tech & Tech of Bamako · NIH-11088171

This project builds a patient registry and consistent care at a Bamako treatment center to improve care for children and adults with sickle cell disease in Mali.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniv of Sciences, Tech & Tech of Bamako NIH-funded
Lab location1 site (Bamako, Mali)
Project IDNIH-11088171 on NIH RePORTER

What this research studies

You would be part of a large effort based at the Centre Recherche et de Lutte contre la Drepanocytose (CRLD) in Bamako that registers up to 4,000 people with sickle cell disease using electronic health records. The team will deliver consistent standards of care (like infection prevention, pain management, and follow‑up) with ongoing quality checks and improvement activities. The work is linked to a Pan‑African sickle cell network supported by NHLBI to share lessons and coordinate care across sites. Researchers will also run observational and implementation studies to find practical ways to expand newborn screening and proven treatments across the region.

Who could benefit from this research

Good fit: People with diagnosed or suspected sickle cell disease in Mali—especially children and families who can access the CRLD center in Bamako—are the ideal candidates to join the registry and receive care.

Not a fit: People without sickle cell disease or those who cannot travel to or access care at the Bamako center are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this could help detect sickle cell earlier and reduce childhood deaths and serious infections by delivering proven preventive care and better follow‑up.

How similar studies have performed: Similar programs using newborn screening, registries, and standardized prophylaxis (vaccines and antibiotics) have reduced deaths in other settings, though wide implementation in sub‑Saharan Africa remains limited.

Where this research is happening

Bamako, Mali

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bacterial Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.