Improving recovery from dialysis-requiring acute kidney injury
Official title: Towards improving recovery from dialysis-requiring acute kidney injury
Funded at University of California, San Francisco · NIH-11035100 · Data updated 2026-11-12
This study is looking for ways to help people with acute kidney injury who need dialysis recover faster and better, by finding markers that show how well their kidneys are healing and trying out new treatments to lessen the time they spend on dialysis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | April 1, 2022 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $201,150 |
| NIH project number | 5K23DK128605-04 |
| Project ID | NIH-11035100 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are hospitalized patients diagnosed with dialysis-requiring acute kidney injury.
✕Less likely to help
Patients with chronic kidney disease or those not requiring dialysis will likely not benefit from this research.
What this research studies
This research investigates ways to enhance recovery for patients suffering from dialysis-requiring acute kidney injury (AKI-D). It aims to identify biomarkers that can predict kidney recovery and evaluate a new treatment approach to reduce the need for prolonged dialysis. The study will involve measuring kidney function through urine tests and testing a combination of treatments to improve patient outcomes. By focusing on these areas, the research seeks to provide better clinical guidelines for managing AKI-D.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery rates for patients with acute kidney injury, reducing the need for long-term dialysis.
How similar studies have gone: Previous research has shown promise in using biomarkers for kidney recovery, but this specific approach is novel and untested.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Mccoy, Ian — University of California, San Francisco
- Study coordinator: Mccoy, Ian
Related research
Other NIH-funded projects on the same topics.
-
SEAK Alliance: Improving Care for AKI Patients in the Southeast
A national, patient-centered effort to improve post-hospital care for people who had acute kidney injury in the Southeast.
-
AKI-related delirium after heart surgery
This grant funds research to understand why some people develop delirium after heart surgery when they also have acute kidney injury.
-
Better ways to identify types of sudden kidney injury in U.S. Veterans
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-
Neuroimmune control of kidney injury using noninvasive ultrasound
A new approach uses targeted ultrasound to gently stimulate nerves and immune signals to help the kidney recover after injury.
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Structure-based approach to prevent kidney injury from polymyxin use
Aims to block how polymyxin damages the kidney so it can be used more safely to treat hard-to-kill infections.
-
How dialysis facility growth affects care for people with end-stage kidney disease
New research will examine whether the spread of dialysis centers and new treatment technologies benefit patients with end-stage kidney disease, and whether benefits reach all communities.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.