Improving PrEP use for women who use drugs in Tanzania

Optimizing PrEP Engagement Among Women Who Use Drugs in Tanzania

NIH-funded research Johns Hopkins University · NIH-11376209

This project helps women who use drugs in Tanzania start and stay on HIV prevention medicine (PrEP) using motivational counseling and cognitive-behavioral support delivered by trained lay counselors.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11376209 on NIH RePORTER

What this research studies

If you are a woman who uses drugs in Dar es Salaam and are worried about HIV, this project adapts two kinds of counseling to help you begin and continue PrEP. Trained paraprofessional counselors will use motivational interviewing focused on PrEP and a brief cognitive-behavioral approach (CETA) to address mental health and substance-use barriers. The team will test whether these counseling supports make it easier for women like you to engage with PrEP services and stick with the medication. Sessions are designed to be delivered locally by counselors with limited prior mental health training.

Who could benefit from this research

Good fit: Ideal participants are adult women who use drugs (for example, heroin) in Dar es Salaam, Tanzania, who are HIV-negative and at risk for HIV and are interested in PrEP.

Not a fit: People living with HIV, men, individuals not using drugs, or those living outside the study area are unlikely to benefit from this specific program.

Why it matters

Potential benefit: If successful, this approach could make it easier for women who use drugs to start and stay on PrEP, lowering their risk of HIV infection.

How similar studies have performed: Motivational interviewing and CETA have helped with substance use, mental health, and some HIV prevention behaviors in other low-resource settings, but combining them specifically to boost PrEP among women who use drugs is relatively new.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAffective DisordersAnxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.