Improving predictions of emotional challenges in preschoolers using brain and behavior data.

Optimizing prediction of preschool psychopathology from brain: behavior markers of emotion dysregulation from birth: A computational, developmental cognitive neuroscience approach

NIH-funded research Northwestern University at Chicago · NIH-10794237

This study is looking for early signs of emotional and behavior challenges in young kids, starting as early as three years old, by examining their brain and behavior from when they were babies, and it aims to create a helpful tool that can predict which children might need extra support to stay healthy and happy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10794237 on NIH RePORTER

What this research studies

This research focuses on identifying early signs of emotional and behavioral challenges in children as young as three years old by analyzing brain and behavior markers from infancy. By utilizing advanced computational methods and data science, the project aims to create a practical risk calculator that can predict the likelihood of preschool psychopathology. The study will pool data from multiple cohorts to develop algorithms that consider both biological and environmental factors affecting mental health. This innovative approach seeks to enhance early intervention strategies and improve outcomes for young children at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research include infants and young children, particularly those with a family history of mental health disorders or early signs of emotional dysregulation.

Not a fit: Patients who are older than preschool age or those without identifiable risk factors for emotional or behavioral challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and intervention for emotional and behavioral issues in preschool-aged children, potentially improving their long-term mental health.

How similar studies have performed: Other research has shown promise in using neurodevelopmental markers for predicting mental health outcomes, indicating that this approach has potential for success.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.