NIH-funded research Sbir 1 grant

Improving personalized care for patients on mechanical ventilation using esophageal pressure measurements

Official title: Decision Support System for Personalized Care of Ventilated Patients using Esophageal Pressure

Funded at Convergent Engineering, INC. · NIH-10921410 · Data updated 2026-11-12

This study is looking at how measuring pressure in the esophagus can help doctors customize breathing support for patients on ventilators, aiming to improve their care and reduce complications.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionConvergent Engineering, INC.
NIH-funded
Lab location1 site (Gainesville, UNITED STATES)
Project startSeptember 15, 2024
Project endSeptember 14, 2025
Funding year2024
Award (this year)$295,924
NIH project number1R43HL170857-01A1
Project IDNIH-10921410 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults who are critically ill and require mechanical ventilation due to conditions like Acute Respiratory Distress Syndrome (ARDS).

Less likely to help

Patients who do not require mechanical ventilation or have conditions unrelated to respiratory distress may not benefit from this research.

What this research studies

This research focuses on enhancing the care of patients who require mechanical ventilation by utilizing esophageal pressure measurements to tailor ventilation strategies to individual needs. By understanding how each patient's respiratory physiology interacts with the ventilator, the research aims to prevent complications such as ventilator-induced lung injury and improve overall outcomes. The approach involves developing a decision support system that simplifies the interpretation of esophageal pressure data, making it easier for healthcare providers to optimize ventilator settings. This personalized method could lead to better management of critically ill patients and reduce the risks associated with mechanical ventilation.

Why it matters

Potential benefit: If successful, this research could significantly improve the safety and effectiveness of mechanical ventilation for critically ill patients.

How similar studies have gone: Previous research has shown that personalized approaches to mechanical ventilation can lead to improved patient outcomes, suggesting that this method may also be effective.

Where this research is happening

  • Convergent Engineering, INC.
    Gainesville, United States
    Active

Researchers

  • Principal investigator: Euliano, Neil R. — Convergent Engineering, INC.
  • Study coordinator: Euliano, Neil R.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.