NIH-funded research NIH-funded research

Improving participation and diversity in gynecologic cancer trials

Official title: Enhancing accrual and diversity across gynecologic and solid tumor trials

Funded at University of Virginia · NIH-10777158 · Data updated 2026-11-12

This study is working to make it easier for women with gynecologic cancers to join clinical trials, so they can access new and better treatments by finding and fixing the obstacles that keep patients and doctors from participating.

More Solid Tumor research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Virginia
NIH-funded
Lab location1 site (Charlottesville, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2024
Award (this year)$135,573
NIH project number1R50CA285360-01
Project IDNIH-10777158 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women diagnosed with gynecologic malignancies who are seeking treatment options through clinical trials.

Less likely to help

Patients with non-gynecologic cancers or those not interested in participating in clinical trials may not benefit from this research.

What this research studies

This research aims to enhance the recruitment and diversity of participants in clinical trials focused on gynecologic cancers. The approach involves identifying and addressing barriers that prevent patients and providers from participating in these trials. The Principal Investigator, who is both a practicing Gynecologic Oncologist and a clinical researcher, will leverage their unique position to foster collaborations and mentorships that promote new clinical trial initiatives. By building a robust clinical research infrastructure, the project seeks to improve access to innovative treatments for women with gynecologic malignancies.

Why it matters

Potential benefit: If successful, this research could lead to more inclusive and effective clinical trials, ultimately improving treatment options for women with gynecologic cancers.

How similar studies have gone: Previous research has shown that targeted efforts to enhance diversity and participation in clinical trials can lead to improved patient outcomes and more representative data.

Where this research is happening

  • University of Virginia
    Charlottesville, United States
    Active

Researchers

  • Principal investigator: Duska, Linda — University of Virginia
  • Study coordinator: Duska, Linda

Related research

Other NIH-funded projects on the same topics.

  • Dual-targeted DOTA CAR T cells with image-guided monitoring for solid tumors

    A Penn team is developing a controllable CAR T cell therapy for solid tumors that can be tracked with PET imaging and guided by targeted agents to improve safety and effectiveness.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11457469

  • Improving patient access to gynecologic cancer trials at UVA

    This grant helps UVA boost enrollment in gynecologic and solid tumor trials so more women with gynecologic cancers can access cutting-edge therapies.

    NIH research University of Virginia · Charlottesville, United States · NIH-11395537

  • Tuning CAR T cells to work better in solid tumors

    A cancer-immunotherapy approach uses specially trained CAR T cells designed to attack solid tumors more effectively and safely.

    NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11384863

  • A 3D lab tool to see how solid tumors squeeze and spread

    This project builds a tiny 3D device that measures how solid tumors push, deform, and let cancer cells break away, which could help people with cancers that form solid tumors.

    NIH research Cornell University · Ithaca, United States · NIH-11286769

  • Dual-target CAR T therapy with PET tracking for solid tumors

    A controllable CAR T-cell treatment that doctors can track with PET scans and direct at solid tumors in adults whose cancers express folate receptors.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11189714

  • Atlas of the tumor environment in childhood cancers

    This project will map the cells and signals surrounding childhood solid tumors like neuroblastoma, rhabdomyosarcoma, and Wilms tumor to find weaknesses that could help children with high-risk disease.

    NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11180224

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.