Improving our understanding of brain injury using combined information
Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization Initiative
This project brings together existing brain imaging and behavioral information from many people with brain injuries to better understand how these injuries affect individuals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project ID | NIH-11140346 on NIH RePORTER |
What this research studies
After a brain injury, people experience a wide range of outcomes, and it's often hard to predict who will recover well and who might face more challenges. Current brain imaging studies are often too small to fully capture all the factors that influence recovery, like age or injury severity. This project aims to solve this by developing special tools and procedures to combine and analyze large amounts of existing brain imaging and behavioral data from many different studies. By doing this, we hope to find clearer patterns and better understand the long-term effects of brain injuries.
Who could benefit from this research
Good fit: This research is relevant to anyone who has experienced an acquired brain injury, as it uses existing data from individuals with this condition.
Not a fit: Patients not directly affected by acquired brain injury may not receive direct benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more accurate predictions of recovery after brain injury and help personalize future treatments.
How similar studies have performed: The ENIGMA consortium has successfully used similar data-sharing and harmonization approaches for over a decade across various clinical disorders.
Where this research is happening
University Park, United States
- Pennsylvania State University, the — University Park, United States (Active)
Researchers
- Principal investigator: Hillary, Frank Gerard — Pennsylvania State University, the
- Study coordinator: Hillary, Frank Gerard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.