NIH-funded research R01 grant

Improving MRI technology for better brain imaging

Official title: Optimized High-Resolution Fast Magnetic Resonance Fingerprinting with Cloud-Based Reconstruction

Funded at Univ of North Carolina Chapel Hill · NIH-10980955 · Data updated 2026-11-12

This study is working on a new way to take clearer and more detailed pictures of the brain using MRI, which could help doctors make better diagnoses and create personalized treatment plans for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 12, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$621,617
NIH project number1R01NS134849-01A1
Project IDNIH-10980955 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals undergoing evaluation for brain-related conditions, such as neurological disorders or tumors.

Less likely to help

Patients with conditions that do not require advanced MRI imaging techniques may not benefit from this research.

What this research studies

This research focuses on enhancing magnetic resonance imaging (MRI) techniques to provide more accurate and detailed images of brain tissue. By utilizing a new method called Magnetic Resonance Fingerprinting (MRF), the team aims to quantify multiple tissue properties simultaneously, which is crucial for diagnosing and monitoring treatment. The project will optimize this technique to achieve high-resolution imaging while reducing the time needed for data acquisition and reconstruction. Patients may benefit from more precise diagnoses and tailored treatment plans based on improved imaging results.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment monitoring for patients with brain disorders.

How similar studies have gone: Previous research has shown promise in improving MRI techniques, but this specific approach using cloud-based reconstruction and MRF is relatively novel.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Yap, Pew-Thian — Univ of North Carolina Chapel Hill
  • Study coordinator: Yap, Pew-Thian

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.