Improving medication safety for children and pregnant women through genetic testing
Supporting Precision Medicine for Maternal and Pediatric Care through Pharmacogenomics Research
This study is looking at how genetic differences in children and pregnant women can change how their bodies process medications, so we can make sure they get the safest and most effective treatments tailored just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10895499 on NIH RePORTER |
What this research studies
This research focuses on understanding how genetic differences affect drug metabolism in children and pregnant women. It aims to validate pharmacogenomic signals, which are crucial for personalized medicine, by using electronic health records to analyze data from diverse populations. The project will also assess knowledge and attitudes towards pharmacogenomic testing among these groups, helping to ensure that the benefits of precision medicine are accessible to all. By addressing gaps in current pharmacogenomic research, this work seeks to improve medication safety and efficacy for vulnerable populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include children under 11 years old and pregnant women, particularly those from diverse and minority backgrounds.
Not a fit: Patients who are not children or pregnant women, or those without chronic diseases, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective medication choices for children and pregnant women based on their genetic profiles.
How similar studies have performed: Previous research in pharmacogenomics has shown promise in improving medication outcomes, but this specific focus on children and pregnant women is relatively novel.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Van Driest, Sara Lynn — Vanderbilt University Medical Center
- Study coordinator: Van Driest, Sara Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.