Improving maternal health for women with lupus through better pregnancy planning.

The HOP-STEP Intervention: Improving Maternal Health in Women with Lupus through Improved Pregnancy Prevention and Planning

['FUNDING_R01'] · DUKE UNIVERSITY · NIH-10658976

This study is all about helping women with lupus plan their pregnancies better and stay healthy by improving the care they receive at clinics, so they can get the right support and information about birth control and pregnancy when they need it.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorDUKE UNIVERSITY (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-10658976 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing pregnancy prevention and planning for women with systemic lupus erythematosus (SLE), a serious autoimmune disease that disproportionately affects young women, especially women of color. The HOP-STEP intervention aims to improve the quality of reproductive health care by restructuring clinic environments to better assess and address patients' contraceptive use and pregnancy intentions. By providing personalized guidance and education, the goal is to help women with SLE achieve healthier pregnancies and reduce the risks associated with unplanned pregnancies. The intervention will also involve training healthcare providers to align their practices with established reproductive health guidelines.

Who could benefit from this research

Good fit: Ideal candidates for this research are women of childbearing age diagnosed with systemic lupus erythematosus.

Not a fit: Patients who are not women or those who do not have systemic lupus erythematosus may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce pregnancy complications and improve maternal and fetal health outcomes for women with lupus.

How similar studies have performed: Previous research has shown that structured interventions in reproductive health care can lead to improved outcomes for women with chronic conditions, indicating potential success for this approach.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Autoimmune Diseases, autoimmune disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.