Improving knee function after ACL surgery using a special treadmill technique

Mi-SPA: Michigan Split-belt Adaptation Paradigm to Improve Knee Loading After Anterior Cruciate Ligament Reconstruction

NIH-funded research University of Michigan at Ann Arbor · NIH-11035197

This study is looking at how walking on a special treadmill, where each leg moves at different speeds, can help people recover better after ACL surgery by improving knee strength and movement, and it’s designed for those who have had this surgery.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11035197 on NIH RePORTER

What this research studies

This research investigates how split-belt treadmill training can help restore normal loading patterns in the knee after anterior cruciate ligament (ACL) reconstruction. Patients will walk on a treadmill where each leg moves at different speeds, which may help increase the strength and function of the surgical knee. The study aims to determine the best training speeds and methods to enhance recovery and prevent future injuries. Participants will be monitored to assess changes in their knee mechanics and overall mobility.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently undergone ACL reconstruction and are experiencing difficulties with knee loading and mobility.

Not a fit: Patients who have not had ACL surgery or those with other severe knee conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved rehabilitation strategies that enhance knee function and reduce the risk of re-injury for patients recovering from ACL surgery.

How similar studies have performed: Previous studies have shown that split-belt treadmill training can effectively modify gait patterns in other populations, but its application in ACL reconstruction patients is novel and untested.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions ACL injuryanterior cruciate ligament injury
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.