Improving joint replacement performance for patients with cartilage damage
Official title: Advancing Hemiarthroplasty: Predicting in vivo performance of cartilage bearing systems through benchtop and ex vivo testing.
Funded at Rhode Island Hospital · NIH-10899572 · Data updated 2026-11-12
This study is looking at different materials used in joint replacement surgery to find the best options that help keep your joints healthy and working well, especially for those with specific cartilage damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rhode Island Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $638,180 |
| NIH project number | 5R01AR082898-02 |
| Project ID | NIH-10899572 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients suffering from localized cartilage damage in their joints, particularly in the wrist or foot.
✕Less likely to help
Patients with widespread joint degeneration or those who do not require hemiarthroplasty may not benefit from this research.
What this research studies
This research focuses on enhancing the performance of hemiarthroplasty, a procedure that replaces damaged joint surfaces with artificial materials. By testing various biomaterials in controlled environments, the study aims to predict how these materials will interact with healthy cartilage over time. The goal is to identify the best materials that can preserve joint function and minimize wear on the opposing cartilage. This research could lead to better outcomes for patients with localized cartilage damage, allowing them to maintain healthier joints.
Why it matters
Potential benefit: If successful, this research could lead to improved joint replacement options that better preserve cartilage and enhance patient mobility.
How similar studies have gone: Previous research has shown promise in improving joint replacement outcomes through the use of advanced biomaterials, indicating that this approach has potential for success.
Where this research is happening
-
Rhode Island Hospital
Providence, United States Active
Researchers
- Principal investigator: Crisco, Joseph J — Rhode Island Hospital
- Study coordinator: Crisco, Joseph J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.