Improving imaging techniques for better diagnosis of heart and eye conditions
Universal optical coherence polarimetry
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11092141
This study is testing a new way to use special imaging technology to get clearer pictures of tissues in the body, which could help doctors better manage heart disease and spot early signs of glaucoma, making it easier for them to use in everyday medical settings.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11092141 on ClinicalTrials.gov |
What this research studies
This research aims to enhance optical coherence tomography (OCT) by integrating advanced polarimetric imaging, which can provide clearer insights into tissue structures. By measuring polarization effects in tissues, this approach seeks to differentiate between types of tissues that are otherwise indistinguishable with standard OCT. This could lead to better management of coronary artery disease and improved detection of early glaucoma symptoms. The project focuses on simplifying the hardware needed for this advanced imaging technique to facilitate its clinical use.
Who could benefit from this research
Good fit: Ideal candidates include patients experiencing acute coronary events or those at risk for glaucoma.
Not a fit: Patients with conditions unrelated to coronary artery disease or glaucoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and improved treatment strategies for patients with coronary artery disease and glaucoma.
How similar studies have performed: Previous research has shown promise in using polarimetric imaging techniques, indicating potential for success in this novel application.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VILLIGER, MARTIN — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: VILLIGER, MARTIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease