Improving heart rhythm treatments with low-energy pacing techniques
Integrative High-Resolution Experimental and Multiscale Modeling of Arrhythmias to Optimize Low Energy Anti-fibrillation Pacing (LEAP)
['FUNDING_R01'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-11063279
This study is exploring a new way to help people with serious heart rhythm problems, like ventricular fibrillation and atrial fibrillation, by using gentle pacing techniques that could lead to safer and more comfortable treatments delivered through a small device.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11063279 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new method to treat dangerous heart rhythms, specifically ventricular fibrillation and atrial fibrillation, using low-energy pacing techniques. By studying heart tissues from patients who have received donor hearts, the researchers aim to create a more effective and less painful treatment protocol that can be delivered through an implantable device. The approach combines advanced modeling and experimental techniques to optimize the pacing required to restore normal heart rhythm while minimizing side effects. Patients may benefit from a safer and more reliable treatment option for their arrhythmias.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with a history of ventricular fibrillation or atrial fibrillation, particularly those who may require implantable devices for heart rhythm management.
Not a fit: Patients who do not have arrhythmias or those whose conditions are not related to ventricular fibrillation or atrial fibrillation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients suffering from life-threatening heart arrhythmias.
How similar studies have performed: Previous research has shown promise in using low-energy pacing techniques for heart rhythm management, indicating potential for success in this novel approach.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FENTON, FLAVIO H — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: FENTON, FLAVIO H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
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