NIH-funded research R21 grant

Improving heart resuscitation methods for children using machine learning

Official title: Evaluating and improving the efficacy of Extracorporeal Cardiopulmonary Resuscitation (ECPR) in pediatric patients using interactive Machine Learning

Funded at Villanova University · NIH-11000848 · Data updated 2026-11-12

This study is looking to improve the chances of survival and brain health for kids who have a cardiac arrest by using smart computer technology to find out which children might benefit the most from a special treatment called ECPR.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionVillanova University
NIH-funded
Lab location1 site (Villanova, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2025
Funding year2025
Award (this year)$111,651
NIH project number5R21HL167181-02
Project IDNIH-11000848 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are hospitalized children under 21 years old who experience cardiac arrest.

Less likely to help

Patients who do not experience cardiac arrest or are outside the pediatric age range may not benefit from this research.

What this research studies

This research focuses on enhancing the effectiveness of Extracorporeal Cardiopulmonary Resuscitation (ECPR) for pediatric patients experiencing cardiac arrest. By utilizing advanced machine learning algorithms, the project aims to analyze a large dataset to identify specific patient characteristics that predict who may benefit from ECPR. The goal is to improve survival rates and neurological outcomes for children who suffer from cardiac arrest, a condition that currently has low survival rates. The research will involve collecting and processing data related to patients' demographics, physiological, and biochemical factors.

Why it matters

Potential benefit: If successful, this research could significantly increase the survival rates and quality of life for children who experience cardiac arrest.

How similar studies have gone: Previous research has shown promising results in using machine learning for improving resuscitation techniques, indicating potential for success in this novel approach.

Where this research is happening

  • Villanova University
    Villanova, United States
    Active

Researchers

  • Principal investigator: Nataraj, Chandrasekhar — Villanova University
  • Study coordinator: Nataraj, Chandrasekhar

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.