Using advanced imaging and AI to assess cognitive decline in older adults

Collaborative Research: SCH: Assessment of Cognitive Decline using Multimodal Neuroimaging with Embedded Artificial Intelligence

NIH-funded research Villanova University · NIH-11091526

This study is working on a new mobile app that uses advanced brain imaging and AI to help doctors better understand and diagnose mild cognitive impairment in older adults, making it easier to find the right care and support for those experiencing memory issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVillanova University NIH-funded
Lab location1 site (Villanova, United States)
Project IDNIH-11091526 on NIH RePORTER

What this research studies

This research focuses on developing a new tool to accurately diagnose and assess cognitive decline, particularly mild cognitive impairment (MCI), in older adults. By utilizing advanced neuroimaging techniques combined with artificial intelligence, the study aims to create a mobile software that can measure brain activity and behavioral responses simultaneously. This innovative approach will help identify biomarkers associated with cognitive decline, leading to better management and treatment options for affected individuals. Patients will be monitored through a combination of functional near-infrared spectroscopy and electroencephalography, providing a comprehensive understanding of their cognitive health.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who may be experiencing symptoms of mild cognitive impairment or are at risk for Alzheimer's disease.

Not a fit: Patients who are not experiencing cognitive decline or do not have risk factors for Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment plans for individuals experiencing cognitive decline.

How similar studies have performed: Previous research has shown promise in using multimodal neuroimaging and AI for cognitive assessments, indicating that this approach could be effective.

Where this research is happening

Villanova, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's disease risk
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.