Improving heart health by treating sleep problems
Strengthening Hearts by Addressing DisruptEd Sleep (SHADES) Mechanistic Trial
This study is looking at how trouble sleeping might affect heart health, and it’s for people with insomnia who will try a special therapy to see if it helps reduce their risk of heart problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10906748 on NIH RePORTER |
What this research studies
This research investigates the link between insomnia and cardiovascular disease (CVD) to identify new prevention strategies. It focuses on understanding how sleep disturbances can lead to heart issues through mechanisms like inflammation and metabolic changes. Patients with insomnia will receive cognitive-behavioral therapy for insomnia (CBT-I) to see if it can lower their risk of developing CVD. The study aims to provide insights into effective interventions that can be integrated into routine care for heart health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who experience insomnia and are at risk for cardiovascular disease.
Not a fit: Patients who do not have insomnia or existing cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that significantly reduce the risk of cardiovascular disease for patients with sleep issues.
How similar studies have performed: Previous research has shown promising results in using cognitive-behavioral therapy for insomnia to reduce inflammation markers associated with cardiovascular disease.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Stewart, Jesse C — Indiana University Indianapolis
- Study coordinator: Stewart, Jesse C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.