Improving heart function during mechanical support for heart failure patients
Optimization of Right and Left Ventricular Coupling During Mechanical Circulatory Support
This study is looking at how the two sides of the heart work together when patients with severe heart failure need mechanical support, with the hope of finding better ways to help them feel better and improve their treatment.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10988236 on NIH RePORTER |
What this research studies
This research investigates how the left and right sides of the heart work together during mechanical support for patients experiencing cardiogenic shock, a severe form of heart failure. By using a novel animal model, the study aims to understand the interactions between the two ventricles and how these interactions affect patient outcomes when using mechanical devices. The goal is to identify key metrics that can guide the selection and adjustment of these devices to improve heart function and patient tolerance. This research could lead to better treatment strategies for patients with severe heart conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from severe heart failure or cardiogenic shock who may require mechanical circulatory support.
Not a fit: Patients with stable heart function or those not requiring mechanical support may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the effectiveness of mechanical circulatory support for patients with heart failure, potentially improving survival rates and quality of life.
How similar studies have performed: Previous research has shown promise in understanding heart function dynamics during mechanical support, but this specific approach to right-left ventricular coupling is relatively novel.
Where this research is happening
Cambridge, United States
- Massachusetts Institute of Technology — Cambridge, United States (Active)
Researchers
- Principal investigator: Lamberti, Kimberly K — Massachusetts Institute of Technology
- Study coordinator: Lamberti, Kimberly K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.