Improving heart disease risk assessment for people living with HIV

Enhancing cardiovascular risk prediction in HIV using novel factors in the REPRIEVE trial

NIH-funded research Massachusetts General Hospital · NIH-11051219

This study is working to create a better way to predict heart disease risk for people living with HIV by looking at different health factors, so that those individuals can get more personalized care and support.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11051219 on NIH RePORTER

What this research studies

This research aims to create a more accurate cardiovascular disease (CVD) risk score specifically for individuals living with HIV. By utilizing data from the REPRIEVE trial, the study will integrate various factors such as inflammatory and immune biomarkers, imaging results, and genetic information to better understand the unique risks faced by this population. The researchers will analyze existing CVD risk prediction scores and their effectiveness in predicting heart disease in people with HIV, ultimately aiming to develop a tailored risk assessment tool that reflects the complexities of HIV-related cardiovascular health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are at risk for cardiovascular disease.

Not a fit: Patients who do not have HIV or those who are not at risk for cardiovascular disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved heart disease prevention strategies for individuals living with HIV.

How similar studies have performed: Previous research has shown that tailored risk assessment tools can improve health outcomes in specific populations, suggesting potential success for this novel approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virusatherosclerotic coronary diseaseAutoimmune Diseasesautoimmune disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.