Improving Harms Reporting in Biomedical Trials to Protect Patients
Official title: SoS: BIO: Improving the Integrity of Harms Reporting in Biomedical Research: A Science-of-Science Framework for Measurement, Causality, and Intervention
Funded at Osu Center for Health Sciences · NIH-11531193 · Data updated 2026-11-12
This grant aims to create reliable measures for how harms are reported in clinical trials so patients can trust the safety information that guides medical decisions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Osu Center for Health Sciences NIH-funded |
| Lab location | 1 site (Tulsa, United States) |
| Project start | August 14, 2026 |
| Project end | April 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $219,557 |
| NIH project number | 1R01GM169341-01 |
| Project ID | NIH-11531193 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers, clinicians, policymakers, and patient advocates interested in improving trial transparency and harm reporting.
✕Less likely to help
Patients are unlikely to experience direct benefits from participation in this grant, as it focuses on methodological improvements.
What this research studies
The project will develop validated metrics to assess how completely and consistently harms are reported in trials and publications. It will map reporting patterns across medical specialties and examine how these patterns affect regulatory actions, guidelines, and scientific influence. The team will pilot practical editorial tools, like flags for discrepancies and harms checklists, to improve reporting practices in real-world settings from 2026 to 2030.
Why it matters
Potential benefit: If successful, it could lead to clearer and more trustworthy safety information for patients and clinicians.
How similar studies have gone: Previous work shows that transparency improvements can change reporting; this project advances beyond audits to reproducible, quantitative measures.
Where this research is happening
-
Osu Center for Health Sciences
Tulsa, United States Active
Researchers
- Principal investigator: Vassar, Matt — Osu Center for Health Sciences
- Study coordinator: Vassar, Matt
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.