Improving function in veterans with anxiety and depression
A New Intervention to Improve Function in Veterans with Anxiety and Depression
This study is looking at a new treatment with a natural substance called pregnenolone to help veterans who are dealing with anxiety and depression, aiming to improve their mood, sleep, and overall well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Durham VA Medical Center NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11052454 on NIH RePORTER |
What this research studies
This research investigates a new treatment approach using a neurosteroid called pregnenolone to help veterans suffering from anxiety and depression. The study aims to address the debilitating effects of these disorders, which often occur together and can lead to increased risks of suicide among veterans. By restoring levels of allopregnanolone, the treatment seeks to alleviate symptoms related to anxiety, depression, sleep disturbances, and pain. Participants will be monitored for improvements in their overall functioning and quality of life.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans experiencing co-occurring anxiety and depression disorders.
Not a fit: Patients who do not have anxiety or depression disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide veterans with a novel treatment option that significantly improves their mental health and daily functioning.
How similar studies have performed: Previous studies have shown promising results with similar neurosteroid treatments in reducing symptoms of anxiety and depression, indicating potential for success in this approach.
Where this research is happening
Durham, United States
- Durham VA Medical Center — Durham, United States (Active)
Researchers
- Principal investigator: Naylor, Jennifer C — Durham VA Medical Center
- Study coordinator: Naylor, Jennifer C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.