Improving early detection of kidney issues in lupus patients with a new test
STTR Phase II: Advance Early Detection of Lupus Nephritis with ClearGold
This study is testing a new urine test called ClearGold to help find kidney problems earlier in people with lupus, so they can get the right treatment sooner and feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clearnano, INC. NIH-funded |
| Lab location | 1 site (Plano, United States) |
| Project ID | NIH-10494086 on NIH RePORTER |
What this research studies
This research focuses on developing a new urine test called ClearGold to detect lupus nephritis, a serious kidney condition that affects many patients with lupus. Currently, the standard method for screening is not sensitive enough, often leading to late diagnosis and treatment. ClearGold aims to provide a more accurate and earlier detection of kidney damage, which could significantly improve patient outcomes. The research involves testing this innovative approach in clinical settings to validate its effectiveness compared to existing methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with systemic lupus erythematosus who are at risk of developing lupus nephritis.
Not a fit: Patients who do not have lupus or those who have already progressed to advanced stages of kidney failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and treatment of lupus nephritis, potentially preventing kidney failure and reducing healthcare costs for patients.
How similar studies have performed: Previous research has shown promise in developing new biomarkers for lupus nephritis, but this approach with ClearGold is considered innovative and has not been widely tested.
Where this research is happening
Plano, United States
- Clearnano, INC. — Plano, United States (Active)
Researchers
- Principal investigator: Yu, Mengxiao — Clearnano, INC.
- Study coordinator: Yu, Mengxiao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.