Improving drug safety and effectiveness through genetic testing.
Official title: Clinical Implementation Resources for Pharmacogenomics (CIRP)
Funded at Stanford University · NIH-10925243 · Data updated 2026-11-12
This study is all about using your genes to help doctors choose the best medications for you, so you get the most benefit and the least side effects, making your treatment safer and more effective.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 8, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,469,999 |
| NIH project number | 5U24HG013077-02 |
| Project ID | NIH-10925243 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are prescribed medications that may be influenced by genetic factors.
✕Less likely to help
Patients who are not taking medications or whose drug responses are not affected by genetic variations may not benefit from this research.
What this research studies
This research focuses on enhancing precision medicine by understanding how genetic variations affect individual responses to medications. It aims to implement pharmacogenomics, which involves using genetic tests to guide drug prescriptions, thereby maximizing treatment efficacy and minimizing adverse effects. The project will develop resources and tools to help healthcare providers interpret genetic data and make informed prescribing decisions. By addressing the significant issue of adverse drug reactions, this initiative seeks to improve patient outcomes and reduce healthcare costs.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of adverse drug reactions and improve the effectiveness of medications for patients.
How similar studies have gone: Previous research has shown success in implementing pharmacogenomics in clinical settings, indicating a promising approach for improving patient care.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Klein, Teri Ellen — Stanford University
- Study coordinator: Klein, Teri Ellen
Related research
Other NIH-funded projects on the same topics.
-
Multimodal AI to predict CAR-T patient response and guide safer, smarter cell design
A Stanford team is building AI tools that use patient and CAR-T cell data to predict how well a CAR-T therapy will work and what design changes might boost effectiveness and safety for people with cancer.
-
Community-driven model to reduce overdose deaths through smarter resource use
A Stanford-led project uses a data-driven model to help counties pick the best ways to prevent opioid and stimulant overdoses and save lives.
-
Center for Dissemination and Implementation at Stanford: Research Core
A Stanford-based program is advancing how evidence-based addiction treatments are implemented across settings to help people with substance use disorders receive better care.
-
Center for Dissemination and Implementation At Stanford (C-DIAS)
A center-based program at Stanford aims to speed people who need addiction treatments to get evidence-based care.
-
Mitochondrial structure and neuron health in Alzheimer's and ALS
This grant studies how mitochondrial cristae structure in neurons is controlled and how its disruption may contribute to diseases like Alzheimer's and ALS.
-
Pediatric EMS seizures: simpler age-based midazolam dosing
A nationwide trial at EMS agencies tests whether using fixed, age-based dosing of midazolam for seizures in children improves treatment speed and safety.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.