Improving drug-coated balloon therapy for peripheral artery disease
Mechanisms of drug-coated balloon therapy
This study is looking at ways to make drug-coated balloons safer and more effective for people with peripheral arterial disease, by testing new designs and materials to improve how the medicine is delivered.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10909993 on NIH RePORTER |
What this research studies
This research investigates how to enhance the effectiveness and safety of drug-coated balloons (DCBs) used in treating peripheral arterial disease (PAD). The team will explore different design strategies, focusing on the surface properties of the balloons and the composition of the drug coatings. By analyzing how these factors affect drug delivery and potential toxicity, they aim to develop next-generation DCBs that could provide better outcomes for patients. The study will utilize advanced modeling techniques to predict the best designs for both immediate and long-term drug release.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with peripheral arterial disease who may benefit from balloon angioplasty treatments.
Not a fit: Patients with conditions unrelated to peripheral arterial disease or those who are not candidates for angioplasty may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients with peripheral arterial disease.
How similar studies have performed: Previous research on drug-eluting devices has shown promise, indicating that innovative approaches in this area can lead to significant advancements in treatment.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Kolachalama, Vijaya B. — Boston University Medical Campus
- Study coordinator: Kolachalama, Vijaya B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.