Improving deep brain stimulation outcomes for Parkinson's disease using MRI data
Prediction of outcomes for deep brain stimulation using multimodal MRI
['FUNDING_OTHER'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11001244
This study is looking to make deep brain stimulation (DBS) better for people with advanced Parkinson's disease by using brain scans and health information to find the best treatment options for each patient, helping them feel better and live more comfortably.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-11001244 on ClinicalTrials.gov |
What this research studies
This research aims to enhance the effectiveness of deep brain stimulation (DBS) for patients with advanced Parkinson's disease by developing a predictive model that integrates clinical data and MRI findings. The approach involves analyzing various factors, including demographics and brain imaging, to better select patients and surgical targets for DBS. By understanding how these predictors influence outcomes, the research seeks to optimize treatment strategies and improve the quality of life for patients. The study will utilize advanced neuroimaging techniques to gather comprehensive data on brain function and structure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with advanced Parkinson's disease who are considering deep brain stimulation as a treatment option.
Not a fit: Patients with early-stage Parkinson's disease or those who are not candidates for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with advanced Parkinson's disease undergoing deep brain stimulation.
How similar studies have performed: Previous research has shown promise in using neuroimaging data to predict outcomes in various neurological treatments, suggesting that this approach may yield beneficial results.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YOUNCE, JOHN ROBERT — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: YOUNCE, JOHN ROBERT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Diseases, Brain Disorders