Improving decision support to prevent drug-related kidney injury in hospitalized patients
(MEnD-AKI) Multicenter Implementation of an Electronic Decision Support System for Drug-associated AKI
This study is looking at ways to help doctors prevent kidney damage from medications in hospitalized adults by using a smart alert system that warns them about patients who might be at risk, and it also involves pharmacists to make sure patients get the best care possible.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11072015 on NIH RePORTER |
What this research studies
This research focuses on reducing the risk of acute kidney injury (AKI) caused by medications in hospitalized adults. It aims to implement an advanced clinical decision support system (CDSS) that alerts healthcare providers about patients at high risk for drug-associated AKI. By optimizing these alerts and integrating pharmacist-led interventions, the study seeks to improve patient outcomes and reduce the incidence of severe kidney damage. The research will also evaluate how physicians perceive the effectiveness of these interventions and their cost-effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are hospitalized adults who are at high risk for acute kidney injury due to nephrotoxic medications.
Not a fit: Patients who are not hospitalized or those who do not receive medications that could potentially harm their kidneys may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the rates of drug-associated acute kidney injury, leading to better health outcomes and reduced mortality for hospitalized patients.
How similar studies have performed: Previous research has shown that clinical decision support systems can effectively reduce adverse drug events, suggesting a promising potential for this approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Kane-Gill, Sandra L — University of Pittsburgh at Pittsburgh
- Study coordinator: Kane-Gill, Sandra L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.