Improving clinical trials for gastroesophageal cancers
Official title: Steering the next generation of NCI-sponsored clinical trials in gastroesophageal cancers
Funded at Massachusetts General Hospital · NIH-10942182 · Data updated 2026-11-12
This study is looking to improve clinical trials for stomach and esophagus cancers by using new treatments based on specific markers, making it easier for patients to join these trials in their communities and ensuring the trials meet their needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 19, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $78,951 |
| NIH project number | 1R50CA291818-01 |
| Project ID | NIH-10942182 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients diagnosed with gastroesophageal adenocarcinomas or other gastrointestinal cancers who are seeking innovative treatment options.
✕Less likely to help
Patients with non-gastrointestinal cancers or those who are not eligible for clinical trials may not benefit from this research.
What this research studies
This research focuses on enhancing the implementation of clinical trials for gastrointestinal cancers, particularly gastroesophageal adenocarcinomas, by utilizing recent advancements in biomarker-directed therapies. The project aims to address critical clinical and scientific questions through the NCI-sponsored clinical trials infrastructure. By evaluating patient demographics and trial feasibility, the research seeks to ensure that trials are effectively tailored to meet the needs of patients. The principal investigator will also work to extend access to these trials in community settings, making participation more convenient for patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options and improved outcomes for patients with gastroesophageal cancers.
How similar studies have gone: Other research has shown success in improving clinical trial implementation and patient outcomes through similar approaches, particularly in the field of gastrointestinal cancers.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Klempner, Samuel J — Massachusetts General Hospital
- Study coordinator: Klempner, Samuel J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.