Improving Care for Children with Liver Disease
Clinical Center for Cholestatic Liver Disease in Children
This research brings together experts to find better ways to care for children with chronic liver conditions like Alagille Syndrome and biliary atresia.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11124877 on NIH RePORTER |
What this research studies
Our center is part of a larger network dedicated to improving the health of children with long-term liver problems. We work with other hospitals and researchers to conduct studies that directly involve patients. This includes developing new clinical studies, analyzing data, and enrolling children in ongoing observational studies. We also process important samples like liver tissue to help understand these diseases better, aiming to advance knowledge and care for these young patients.
Who could benefit from this research
Good fit: Children diagnosed with cholestatic liver diseases, such as Alagille Syndrome, biliary atresia, mitochondrial hepatopathies, or primary sclerosing cholangitis, especially those aged 0-11 years, would be ideal candidates.
Not a fit: Patients without a diagnosis of a chronic cholestatic liver disease or those outside the pediatric age range may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this collaborative effort could lead to new treatments and improved care strategies for children suffering from chronic liver diseases.
How similar studies have performed: This work builds upon a strong foundation of previous successful patient-based studies and collaborative efforts within the Childhood Liver Disease Research Network.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Miethke, Alexander — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Miethke, Alexander
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.