Improving brain stimulation treatments for depression and migraines
Precision TMS with integrated visualization and analysis of real-time E-field and EEG source imaging
['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11048069
This study is working on making a brain treatment called transcranial magnetic stimulation (TMS) even better by using new software that helps doctors customize the treatment for each person based on their unique brain structure and activity, aiming to help people with conditions like depression and migraines feel better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11048069 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing transcranial magnetic stimulation (TMS), a treatment for various brain disorders, by developing advanced software that allows for real-time mapping of electric fields and EEG analysis. By personalizing the treatment parameters based on individual brain anatomy and function, the study aims to improve the effectiveness of TMS for conditions like major depressive disorder and migraines. The approach involves using diffusion MRI and EEG data to accurately target specific brain regions, thereby optimizing treatment outcomes for patients. Through this innovative methodology, the research seeks to address the variability in patient responses to TMS.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with major depressive disorder, obsessive-compulsive disorder, migraines, or those seeking to quit smoking.
Not a fit: Patients with conditions not related to brain disorders or those who do not respond to TMS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients suffering from depression, migraines, and other brain disorders.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to enhance TMS efficacy, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NING, LIPENG — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: NING, LIPENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Diseases, Brain Disorders