Improving brain stimulation techniques for treating depression
Optimized methods for measuring brain excitability in depression
['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-11102105
This study is looking to improve treatment for depression by finding better ways to measure how the brain responds to a special therapy called rTMS, so that each person's treatment can be customized for the best results.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11102105 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the effectiveness of repetitive transcranial magnetic stimulation (rTMS) for depression by developing reliable methods to measure brain excitability. It aims to identify specific markers of prefrontal cortex activity that can guide personalized treatment approaches. By utilizing a new system called TARGET, the study will dynamically adjust stimulation parameters to optimize treatment outcomes based on individual brain responses. This could lead to more effective and tailored therapies for patients suffering from depression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with depression who may benefit from rTMS treatment.
Not a fit: Patients who do not have a diagnosis of depression or those who have contraindications for rTMS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for depression, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using TMS for depression, but this approach aims to refine and enhance existing methods, making it a novel advancement in the field.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KELLER, COREY J — STANFORD UNIVERSITY
- Study coordinator: KELLER, COREY J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Diseases, Brain Disorders