Improving Brain Imaging for Partial Epilepsy
Electrophysiological Source Imaging of Partial Epilepsy
This project aims to create a new, non-invasive way to find the exact brain areas causing seizures in people with partial epilepsy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Carnegie-Mellon University NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11126875 on NIH RePORTER |
What this research studies
For people with partial epilepsy, finding the precise area of the brain causing seizures is crucial for successful surgery. Currently, this often involves invasive procedures where electrodes are placed directly inside the brain. This project is developing a new, non-invasive brain imaging technique that uses advanced computer analysis of standard EEG recordings. The goal is to accurately pinpoint the seizure-causing areas without needing surgery, making pre-surgical planning safer and more comfortable. This new method will be tested extensively with over 120 patients to ensure it works as well as or better than current invasive approaches.
Who could benefit from this research
Good fit: Patients with focal (partial) epilepsy who are candidates for or considering epilepsy surgery would be ideal.
Not a fit: Patients whose epilepsy is not focal or who are not candidates for surgical intervention may not directly benefit from this specific imaging technique.
Why it matters
Potential benefit: If successful, this could offer a safer, more comfortable, and highly accurate way to identify seizure-causing brain areas for patients considering epilepsy surgery.
How similar studies have performed: This project proposes a novel unsupervised machine learning framework for this specific application, building on existing knowledge of EEG and high-frequency oscillations.
Where this research is happening
Pittsburgh, United States
- Carnegie-Mellon University — Pittsburgh, United States (Active)
Researchers
- Principal investigator: He, Bin — Carnegie-Mellon University
- Study coordinator: He, Bin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.