NIH-funded research NIH-funded research

Improving blood flow in stroke patients with large vessel occlusion

Official title: Extending the Ischemic Penumbra in Large Vessel Occlusion Stroke

Funded at Shearit, LLC · NIH-10820012 · Data updated 2026-11-12

This study is looking at a new way to help people who have had a serious type of stroke by using a special treatment called Lamiflo™ that improves blood flow, and it's for patients who might be eligible based on their imaging results.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionShearit, LLC
NIH-funded
Lab location1 site (Albuquerque, United States)
Project startSeptember 10, 2024
Project endAugust 31, 2025
Funding year2024
Award (this year)$490,049
NIH project number1R41NS129388-01A1
Project IDNIH-10820012 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients experiencing large vessel occlusion acute ischemic stroke who meet specific imaging criteria.

Less likely to help

Patients who do not have large vessel occlusion or those who do not meet the imaging criteria may not benefit from this research.

What this research studies

This research investigates a new treatment approach for patients experiencing large vessel occlusion acute ischemic stroke. It focuses on using a unique polymer, Lamiflo™, which enhances blood flow dynamics without relying on traditional pharmacological methods. By qualifying patients through imaging, the study aims to identify those who could benefit from this innovative treatment, potentially increasing the number of patients eligible for effective intervention. The goal is to protect brain tissue and improve outcomes for stroke patients.

Why it matters

Potential benefit: If successful, this research could significantly improve recovery outcomes for stroke patients by enhancing blood flow to affected brain areas.

How similar studies have gone: While traditional neuroprotection trials have faced challenges, this novel approach using Lamiflo™ represents a new direction that has not been extensively tested in clinical settings.

Where this research is happening

  • Shearit, LLC
    Albuquerque, United States
    Active

Researchers

  • Principal investigator: Nemoto, Edwin M — Shearit, LLC
  • Study coordinator: Nemoto, Edwin M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.