Improving antibody-gold nanoparticle interactions for better diagnostics
Official title: Supplemental Funds for SPR Instrument
Funded at Illinois State University · NIH-11027834 · Data updated 2026-11-12
This study is working on making better tools for medical tests by improving how antibodies are attached to tiny gold particles, which could help make tests more accurate for diagnosing different health conditions.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Illinois State University NIH-funded |
| Lab location | 1 site (Normal, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $89,008 |
| NIH project number | 3R15GM146167-01S1 |
| Project ID | NIH-11027834 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research include those requiring advanced diagnostic testing for various diseases.
✕Less likely to help
Patients who do not require diagnostic testing or have conditions that are not addressed by antibody-gold nanoparticle technologies may not benefit.
What this research studies
This research focuses on enhancing the stability and effectiveness of antibody-gold nanoparticle (AuNP) conjugates, which are crucial for diagnostic tests. The team aims to develop a method for attaching antibodies to gold nanoparticles in a way that maintains their activity and stability. By using enzyme-mediated techniques, they plan to create highly active and oriented antibody-gold nanoparticle conjugates that can improve the accuracy of immunoassays. This work could lead to more reliable diagnostic tools for various medical conditions.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and reliable diagnostic tests for patients.
How similar studies have gone: Previous research has shown promise in enhancing antibody-nanoparticle interactions, suggesting potential for success in this novel approach.
Where this research is happening
-
Illinois State University
Normal, United States Active
Researchers
- Principal investigator: Driskell, Jeremy D. — Illinois State University
- Study coordinator: Driskell, Jeremy D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.