Improving Antibiotic Treatments for Long-Term Infections
Strategies for improving the efficacy of combinatorial antibiotic therapy in chronic infections
['FUNDING_R01'] · TEXAS TECH UNIVERSITY · NIH-11097281
This project looks for better ways to use combinations of antibiotics to fight stubborn, long-lasting infections that are hard to treat.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS TECH UNIVERSITY (nih funded) |
| Locations | 1 site (LUBBOCK, UNITED STATES) |
| Trial ID | NIH-11097281 on ClinicalTrials.gov |
What this research studies
The spread of antibiotic resistance is a growing concern, especially for chronic infections like those in wounds and lungs. This research aims to understand why current antibiotic treatments often fail against these persistent infections. We will explore how bacteria evolve resistance and how different types of bacteria interact within an infection, which can make treatments less effective. By understanding these complex factors, we hope to design new and more powerful antibiotic combinations to clear these difficult infections.
Who could benefit from this research
Good fit: Patients with chronic bacterial infections, especially those in wounds or lungs, who have experienced difficulty with current antibiotic treatments, might eventually benefit from this research.
Not a fit: Patients without chronic bacterial infections or those whose infections are easily cleared by existing treatments may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more effective antibiotic treatments for chronic infections, helping patients recover fully and reducing the risk of antibiotic resistance.
How similar studies have performed: While combination antibiotic therapies are common, this research focuses on novel strategies to overcome resistance in chronic infections, suggesting a new or refined approach.
Where this research is happening
LUBBOCK, UNITED STATES
- TEXAS TECH UNIVERSITY — LUBBOCK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WAKEMAN, CATHERINE ANN — TEXAS TECH UNIVERSITY
- Study coordinator: WAKEMAN, CATHERINE ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections